Product name: | HCG |
CAS No.: | 12629-01-5 |
Specification: | 5000iu/vial 10vials/kit |
Appearance: | White powder |
Form & Formulations: | Sterile Filtered white lyophilized (Freeze-Dried) |
Purity: | >98% by RP-HPLC |
Water Content: | ≤ 7.0% by Karl Fischer |
Acetate Content: | ≤ 10.0% by RP-HPLC |
Bacterial Endotoxins: | ≤ 5EU/mg |
Suitability: | Suitable for cell culture and human experiment |
Storage: | 2-8 degree centigrade refrigerator |
Delivery: | 1 working day for ready goods,7 days to your destination. |
Package: | 1kit=10vials Aluminum foil+bubble+carton |
Customized: | accepted. |
Country of Origin: | China |
HCG contains human chorionic gonadotropin (HCG). HCG is a naturally occurring hormone produced by the placenta. It is indicated for the induction of ovulation and pregnancy in the anovulatory, infertile women in whom the cause of anovulation is secondary and not due to primary ovarian failure.
Human chorionic gonadotropin (hCG) is a hormone produced by the placenta after implantation.The presence of hCG is detected in some pregnancy tests (HCG pregnancy strip tests). Some cancerous tumors produce this hormone; therefore, elevated levels measured when the patient is not pregnant may lead to a cancer diagnosis and, if high enough, paraneoplastic syndromes, however, it is not known whether this production is a contributing cause, or an effect of carcinogenesis. The pituitary analog of hCG, known as luteinizing hormone (LH), is produced in the pituitary gland of males and females of all ages.
Human chorionic gonadotropin is glycoprotein composed of 237 amino acids with a molecular mass of 36.7 kDa, approximately 14.5 αhCG and 22.2kDa βhCG.
It is heterodimeric, with an α (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and β (beta) subunit that is unique to hCG.
The α (alpha) subunit is 92 amino acids long.
The β-subunit of hCG gonadotropin (beta-hCG) contains 145 amino acids, encoded by six highly homologous genes that are arranged in tandem and inverted pairs on chromosome 19q13.3 - CGB (1, 2, 3, 5, 7, 8)
The two subunits create a small hydrophobic core surrounded by a high surface area-to-volume ratio: 2.8 times that of a sphere. The vast majority of the outer amino acids are hydrophilic.
As you get further along in pregnancy and the hCG level gets higher, the time it takes to double can increase to about every 96 hours.
Caution must be used in making too much of hCG numbers. A normal pregnancy may have low hCG levels and result in a perfectly healthy baby. The results from an ultrasound after 5 -6 weeks gestation are much more accurate than using hCG numbers.
An hCG level of less than 5 mIU/mL is considered negative for pregnancy, and anything above 25 mIU/mL is considered positive for pregnancy.
An hCG level between 6 and 24 mIU/mL is considered a grey area, and you’ll likely need to be retested to see if your levels rise to confirm a pregnancy.
The hCG hormone is measured in milli-international units per milliliter (mIU/mL).
A transvaginal ultrasound should be able to show at least a gestational sac once the hCG levels have reached between 1,000 – 2,000 mIU/mL. Because levels can differentiate so much and conception dating can be wrong, a diagnosis should not be made by ultrasound findings until the hCG level has reached at least 2,000 mIU/mL.
A single hCG reading is not enough information for most diagnoses. When there is a question regarding the health of the pregnancy, multiple testings of hCG done a couple of days apart give a more accurate assessment of the situation.
The hCG levels should not be used to date a pregnancy since these numbers can vary so widely.
There are two common types of hCG tests. A qualitative hCG test detects if hCG is present in the blood. A quantitative hCG test (or beta hCG) measures the amount of hCG actually present in the blood.
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